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School of Biological and Chemical Sciences

SBCS




Dr Romila Devi Gopalan

 

BSc S.Pac., MBioMedSc Monash

Lecturer in Organic Chemistry

FSTE-N244

Ph: +679-3232446

Teaching

I contribute in following courses:

CH102- reaction in alcohols, amines and carbonyl compounds

CH201- reactions involved with aromatic compounds and 1H NMR

CH303- Carbon-carbon bond formation reactions, herbicides, pesticides and pharmaceuticals

CH301- UV, IR, 1HNMR, 13CNMR spectroscopy and Mass spectrometry

CH405- Proteins- structure and function

CH413- Biosynthetic pathways involved in secondary metabolite synthesis

CH414- Advanced spectroscopy involved in organic chemistry

 

Current Research interests

1.      De novo design of peptides with desired structural and biological applications.

 

2.      Isolation, characterisation and biological application of bioactive compounds from plants sources.

 

3.      Isolation of proteins from waste animal sources for biological applications.

 

4.       Study of folate levels in various foods in the Pacific.

 

Current MSc Students

1.      Prayna Maharaj

Title of project:  Folate levels in cooked food using salt and lemon juice as food additives.

 

2.      Komal Shandil

Title of project: Isolation, characterisation and biological application of bioactive compounds from noni.

 

 

Publications

·Gopalan, R. D.; Del Borgo, M. P.; Bergman, Y. E.; Unabia, S.; Mulder, R.J.; Wilce, M. C.J.; Wilce, J. A.; Marie-Isabel Aguilar, M.-I.; Perlmutter, P., 2012, Conformational Stability Studies of a Stapled Hexa-β3-Peptide Library, Organic and Biomolecular Chemistry, First published on the web: 18th Jan, 2012.

 

·Bergman, Y. E.; Del Borgo, M.; Unabia, S.; Jalal, S.; Ciampini, M.; Clayton, D.; Gopalan, R. D.; Fletcher, J. M.; Mulder, R. J.; Wilce, J. A.; Aguilar, M. I. and Perlmutter, P., 2009, Synthesis of Ring Closing Metathesis-Stapled β3-Peptides., Organic Letters, 11, 4438-4440.

 

·Aguilar, M.-I.; Purcell, A.W.; Devi, R.; Lew, R.; Purcell, A.W.; Rossjohn, J.; Smith, A. I.; and Perlmutter, P., 2007, β-Amino Acid-Containing Hybrid Peptides–New Opportunities in Peptidomimetics Organic and Biomolecular Chemistry, 5, 2884-2890.

 

·Gopalan, R D., 2007, Organic Chemistry, In Form Seven Chemistry, 3rd Ed, Chemical Society of the South Pacific Publications, (Khurma & Nand, Ed), 106-154.

 

·Smith, A I.; Lew, R. A.; Perlmutter, P.; Devi, R. and Aguilar, M -I., 2004, The Application of Beta-Amino Acid based Peptidomimetics as Molecular templates for Drug Design. Peptide Science-The Japanese Peptide Society (Y. Shimohigashi (Ed)), 47-50.

 

 

Conferences

·Romila D. Gopalan, Ylva Bergman, Mibel Aguilar and Patrick Perlmutter, A safe and convenient method for the synthesis of Fmoc-β3-amino acids in the design and synthesis of functionalised 14-helical hexa-β3-peptides, 36th Annual Synthesis Symposium, Melbourne, Australia, 2nd December, 2011.

 

·Gopalan, R. D.; Del Borgo, M. P.; Bergman, Y. E.; Unabia, S.; Mulder, R.J.; Wilce, M. C.J.; Wilce, J. A.; Marie-Isabel Aguilar, M.-I.; Perlmutter, P., 31st European Peptide Symposium, Bella Center, Copenhagen, Denmark. 5-9th September 2010.

 

·Gopalan, R. D.; Del Borgo, M. P.; Bergman, Y. E.; Unabia, S.; Wilce, M. C.J.; Wilce, J. A.; Marie-Isabel Aguilar, M.-I.; Perlmutter, P., Australian Peptide Conference, Gold Coast, October 11-16, 2009

 

·Patel, K; Gopalan, R. D.; Ali, S.; Sotheeswaran, S.; Essential Oils of Some Fijian Medicinal plants, IVth International Conference on Aromatic and Medicinal Plants from French Overseas regions, Tahiti, July 10-13, 2006.

 

·Aguilar M., Devi  R., Branson K., Stewart K., Lew R., Harte M., Perlmutter P., Smith I., Inhibitors of Aminopeptidase P Incorporating beta Amino acids, Proceedings of the 27th European Peptide Symposium, Sorrento, Italy, 31st Aug –6th Sept, 2002.


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